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Full information on isolate PW8 (id:24)

Projects

This isolate is a member of the following projects:

cgMLST set-up study
Isolates included in the cgMLST study (Guglielmini et al. J CLin Microbiol 2021 https://pubmed.ncbi.nlm.nih.gov/34524891/)
ResistanceGenomics
Hennart et al. 247 isolates dataset
Hennart_diphtOscan_2023_OtherIsolates
Publicly-available genomes and isolates from the French NRC (2018-2021)
DelgadoBlas_LINcodes_2025
Dataset of 1,665 isolates of C. diphtheriae, C. belfantii and C. rouxii used for the population structure analysis of C. diphtheriae sensu lato.

Provenance/primary metadata

id
24
isolate
PW8
alias
ASM25527v1
species
C. diphtheriae
biovar
Mitis
tox gene PCR
Positive
tox production Elek
Positive
isolation year
1896
city
New York
country
USA
continent
North America
travel history
Not documented
host
Human
source
Respiratory
infection or disease
Diphtheria
comments
Strain used for toxoid vaccine production
accession number
CP003216
epidemic cluster
cryptic_6
sender
Melody Dazas, Institut Pasteur
curator
Auto Tagger
update history
1312 updates show details
date entered
2017-02-07
datestamp
2025-07-18

Publications (4)

  • Guglielmini J, Hennart M, Badell E, Toubiana J, Criscuolo A, Brisse S (2021). Genomic Epidemiology and Strain Taxonomy of Corynebacterium diphtheriae. J Clin Microbiol 59:e0158121
  • Hennart M, Panunzi LG, Rodrigues C, Gaday Q, Baines SL, Barros-Pinkelnig M, Carmi-Leroy A, Dazas M, Wehenkel AM, Didelot X, Toubiana J, Badell E, Brisse S (2020). Population genomics and antimicrobial resistance in Corynebacterium diphtheriae. Genome Med 12:107
  • Striga M, Curković T, Vukas Z (1990). Combined technique of argon-laser and neodymium-YAG laser photocoagulation for narrow-or closed-angle glaucoma. Acta Med Iugosl 44:521-32
  • Trost E, Blom J, Soares Sde C, Huang IH, Al-Dilaimi A, Schröder J, Jaenicke S, Dorella FA, Rocha FS, Miyoshi A, Azevedo V, Schneider MP, Silva A, Camello TC, Sabbadini PS, Santos CS, Santos LS, Hirata R, Mattos-Guaraldi AL, Efstratiou A, Schmitt MP, Ton-That H, Tauch A (2012). Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia. J Bacteriol 194:3199-215

Sequence bin

method
Unknown
contigs
1
length
2,530,683 bp
%GC
53.70
Ns
0
gaps
0
loci tagged
1,375

Show sequence bin

Assembly checks

CheckStatusWarn/fail reason
Number of contigs
Assembly size
Minimum N50
%GC

Analysis

rMLST species identification

RankTaxonTaxonomySupportMatches
SPECIES Corynebacterium diphtheriae Actinomycetota > Actinomycetes > Mycobacteriales > Corynebacteriaceae > Corynebacterium > Corynebacterium diphtheriae 100%

Analysis performed: 2025-06-05

Similar isolates (determined by LIN codes)

Scheme
cgMLST
LIN code
0_0_196_0_0_0_0_0_0_0
Species
C. diphtheriae
Lineage
0_0
Sublineage
SL44
Clonal group
ClG44
Genetic cluster
GC63

Show all thresholds

PrefixThresholdMatching isolates
0_0_196_0_0_081
0_0_196_0_0_0_041
0_0_196_0_0_0_0_021
0_0_196_0_0_0_0_0_011
0_0_196_0_0_0_0_0_0_001
012202380
0_010352162
0_0_1965006
0_0_196_0556
0_0_196_0_0256
0_0_196_0_0_081
0_0_196_0_0_0_041
0_0_196_0_0_0_0_021
0_0_196_0_0_0_0_0_011
0_0_196_0_0_0_0_0_0_001

Similar isolates (determined by classification schemes)

Experimental schemes are subject to change and are not a stable part of the nomenclature.

Classification schemeUnderlying schemeClustering methodMismatch thresholdStatusGroupFields
SublineagecgMLSTSingle-linkage500experimental20 (6 isolates)
SL: 44
Genomic_clustercgMLSTSingle-linkage25experimental20 (6 isolates)
SublineagecgMLSTSingle-linkage500experimental20 (6 isolates)
SL: 44
Genomic_clustercgMLSTSingle-linkage25experimental20 (6 isolates)

Schemes and loci

Navigate and select schemes within tree to display allele designations

Tools

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